Wolman was the first recipient of the Pearse Prize for Histochemistry awarded by the Royal Microscopical Society ( Wolman, 1989 ) and also received the Pioneer Award of the International Federation of Histochemical Societies ( Carpenter, 1990 ).
32.
Histochemical and immunohistochemical analyses at the single-fiber level clearly show that the atrophic process seen at the gross level is due to a reduction in the diameter of the affected myofibers of which the individual muscles are composed.
33.
Using a histochemical marker for a protein known to be involved in the processing of pain, they were able to label the nerve fibres at the perimeter of the papilla, suggesting that they are nociceptive, i . e . they respond to pain.
34.
Lastly, osteogenic differentiation was visible through calcium accumulation after one week . " The sensitive RT-PCR assays, in addition to the immunological and histochemical data, showed that neither the adipogenic nor the osteogenic cultures were composed of cells of multiple lineages.
35.
Both structures share histochemical homology with reptilian scales, however work on their evolutionary development has revealed that the scales in bird feet have secondarily evolved via suppression of the feather-building genetic program Unblocking the feather suppression program results in feathers growing in place of scales along the tarsometatarsus and toes.
36.
Unfortunately, there is evidence that immunohistochemical EGFR receptor testing does not predict response to either cetuximab or panitumumab, so that this has been called a " misleading biomarker " that has nevertheless caused insurers and even health systems to deny payment for EGFR antibody treatment for patients who lack a positive tumor EGFR histochemical test.
37.
He earned a Ph . D . in Pharmacology ( 1953 ), a BM ChB in Medicine ( 1958 ) and a D . M . degree ( 1964 ) at Magdalen & Balliol College Oxford where he won the prestigious Radcliffe Prize for Medical Research for his histochemical investigations on cholinesterase and amine oxidase in the skin.
38.
INOS ( inducible nitric oxide synthase ) is an enzyme responsible for the production of NO, an important molecule used by macrophages to kill infected cells . ( Abbas and Lichtman, 2005 ) A decrease in the levels of iNOS, ( as seen through immuno histochemical staining ) has been observed in IFN? " / " mice although levels of macrophages at the site of tumor challenge are similar to wild type mice.
39.
He served for many years as a Director of the Cornell University Research Foundation, Inc . He was a member of Sigma Xi, Phi Kappa Phi, and Phi Zeta; a Fellow of the American Association for the Advancement of Science, a member of the American Association of Anatomists, the American Society of Mammalogists, the Histochemical Society, the Society for the Study of Reproduction, and the American Society of Zoologists.
40.
Analysis of the muscle biopsy samples with a variety of morphologic, histochemical, and biochemical techniques indicated that the myofiber CSA was significantly decreased after spaceflight; that atrophy was greatest in Type IIB myofibers, followed by Type IIA and then Type I myofibers; that expression of Type II myosin heavy chain ( MHC ) protein was significantly increased, with an apparent decrease in the amount of Type I MHC protein expressed; and that the number of myonuclei per mm of myofiber length was significantly decreased in Type II myofibers after 11 days of spaceflight.
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