31. Rare side effects include hypersensitivity reactions causing difficulty breathing. 32. Sulfamethoxazole is contraindicated in people with a known hypersensitivity to trimethoprim or sulfonamides. 33. Treatment may have adverse effects by causing scarring, dermatitis, or hypersensitivity . 34. It appears to be effective in reducing tooth hypersensitivity . 35. Roosevelt soon exhibited an illness characterized by fever, hypersensitivity of the skin. 36. These hypersensitivity reactions to tetrazepam share no cross-reactivity with other benzodiazepines. 37. Also, unlike asthma, hypersensitivity pneumonitis targets lung alveoli rather than bronchi. 38. Together with Robin Coombs, he developed the Gell Coombs classification of hypersensitivity . 39. Hypersensitivity reactions can include anaphylactoid and anaphylactic reactions ranging from mild to severe.40. Hypersensitivity and pleasure-response are not the only physical responses to opiates.