31. In case of puberty menorrhagia due to immaturity of hypothalamic axis, hormonal therapy is beneficial. 32. Together, these findings suggest abnormality in the hypothalamic -pituitary-adrenal ( HPA ) axis. 33. However, SSRI therapy represents a possible hormonal solution to just one hormonal condition of hypothalamic amenorrhoea. 34. FSH is subject to oestrogen feed-back from the gonads via the hypothalamic pituitary gonadal axis. 35. The other major player in the acute stress response is the hypothalamic -pituitary-adrenal axis. 36. The stria terminalis extends from the region of the hypothalamic , and thalamic areas of the brain. 37. This gene was first identified in the hypothalamic -pituitary-adrenal axis ( HPA axis ). 38. Weight loss can cause elevations in the hormone ghrelin which inhibits the hypothalamic -pituitary-ovarial axis. 39. After switching off the blue light, the hypothalamic orexin neurons showed activity for several tens of seconds. 40. Emerging data suggests that THC acts via CB 1 receptors in the hypothalamic nuclei to directly increase appetite.