31. It has been hypothesised that Franks'sign is indicative of cardiovascular disease and / or diabetes. 32. Some scholars have hypothesised that Ducetius returned without the consent of Syracuse, but this is very improbable. 33. He hypothesised that schizophrenics may lack the ability to remove the hallucinogenic catecholamine metabolite adrenochrome from their brains. 34. Through these early experiments he started to hypothesise about the role of mosquitoes and the spread of disease. 35. Specifically it is hypothesised that MACPF proteins oligomerise to form a large circular pore ( figure 2 ). 36. He directs his attention to the effects of sugar and in particular on its hypothesised role in diabetes. 37. A wide range of natural phenomena have been hypothesised , including otters, swimming deer, and unusual waves. 38. Admittedly, he may only have been hypothesising a theoretical eventuality and not attempting a Franco-Spanish union. 39. Yule et al . hypothesised that some of these differences may be due to discrimination and other societal factors. 40. It has been hypothesised that Chimnechild was not Dagobert's mother, thus her reason for abandoning him.