:: : : Ketamine is a good example of a drug that can be administered in numerous different ways, either by ingesting, insufflating, injecting intravenously and intramuscularly, etc . Erowid has a good chart on the efficiency of each route of administration.
32.
Drug dealers selling heroin to users who inject dilute the drug with different products from dealers selling to users who smoke or insufflate the drug; diluents which can easily form a solution with water for injecting heroin can be problematic for users who are sniffing the powder.
33.
Other means of ingestion such as vaporizing, injecting, or insufflating the drug can produce powerful hallucinations for a short time ( usually less than half an hour ), as the DMT reaches the brain before it can be metabolized by the body's natural monoamine oxidase.
34.
Marc Klowden, the entomologist at the University of Idaho who did these insufflating experiments, also has videos showing what happens when you prevent the signal from the abdominal receptors from reaching the brain : Too much is never enough for these mosquitoes, and they eat until they explode.
35.
During laparoscopy ( laparoscopic surgery or minimally invasive surgery ), it is necessary to insufflate the abdominal cavity ( i . e . inflate the abdomen like a balloon ) with medical-grade carbon dioxide ( CO 2 ) to create a viewing and working space for the surgery.
36.
Crystal methamphetamine and salts of amphetamine are sometimes powdered and insufflated by recreational users, which results in a fairly rapid uptake of the drug through the nasal epithelium; with regular use, amphetamine or methamphetamine insufflation slowly damages and eventually destroys the nasal septum due to their causticity and vasoconstrictive effects.
37.
Under ideal conditions ( i . e ., if pure oxygen is breathed before onset of apnea to remove all nitrogen from the lungs, and pure oxygen is insufflated ), apneic oxygenation could theoretically be sufficient to provide enough oxygen for survival of more than one hour's duration in a healthy adult.
38.
"Those who are to be baptised are insufflated by the priest of God, so that the Prince of Sinners [ i . e . the devil ] may be put to flight from out of them, and that entry for the Lord Christ might be prepared, and that by his insufflation they might be made worthy to receive the Holy Spirit ."
39.
He left campus at approximately 2 AM on Thursday, June 19 and drove to an off-campus gathering, which he attended briefly before returning to his dorm in Washington Hall sometime between 2 : 30 and 3 AM . For the next 3 to 4 hours, Bias, long-time friend Brian Tribble, and several teammates repeatedly insufflated cocaine in the dormitory suite shared by Bias and his teammates.
40.
When insufflated, the onset happens very rapidly, usually reaching the peak at about 20 40 minutes and plateauing for 2 3 hours . 2C-B is also considered one of the most painful drugs to insufflate, with users reporting intense nasal burning The sudden intensity of the experience combined with the pain can often start the experience with a negative imprint and nausea is also increased with insufflation, compounding the issue.
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