Members of the mitochondrial carrier family are involved in transporting keto acids, amino acids, nucleotides, inorganic ions and co-factors across the mitochondrial inner membrane.
32.
?-Ketobutyric acid is transported into the mitochondrial matrix, where it is converted to propionyl-CoA by branched-chain alpha-keto acid dehydrogenase complex.
33.
Branched-chain keto acid dehydrogenase is a multienzyme complex associated with the inner membrane of mitochondria, and functions in the catabolism of branched-chain amino acids.
34.
The production of glucose from glucogenic amino acids involves these amino acids being converted to alpha keto acids and then to glucose, with both processes occurring in the liver.
35.
Transaminases require the coenzyme pyridoxal-phosphate, which is converted into pyridoxamine in the first phase of the reaction, when an amino acid is converted into a keto acid.
36.
As suggested by the name of the family, LAAOs are products are the corresponding ?-keto acid ( 2-oxo acid ), ammonia, and hydrogen peroxide.
37.
Its toxicity stems primarily from the fact that it readily forms oximes with keto acids and aldehydes, especially the pyridoxal phosphate cofactor of many vitamin B 6-dependent enzymes.
38.
The complex consists of multiple copies of 3 components : branched-chain alpha-keto acid decarboxylase ( E1 ), lipoamide acyltransferase ( E2 ), and lipoamide dehydrogenase ( E3 ).
39.
The starter unit for the biosynthesis of streptogramin A is isobutyryl-CoA, which is given by the amino acid valine after it has undergone transamination and branched-chain keto acid dehydrogenation.
40.
"' Phenylpyruvic acid "'is the organic compound with the formula C 6 H 5 CH 2 C ( O ) CO 2 H . It is a keto acid.
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