In rare chronic forms of lactic acidosis caused by mitochondrial disease, a specific diet or dichloroacetate may be used.
32.
More commonly, infants with GSD I tolerate without obvious symptoms a chronic, mild hypoglycemia, and compensated lactic acidosis between feedings.
33.
Lactic acidosis is initially treated with sodium bicarbonate, although high doses are not recommended, as this may increase intracellular acidosis.
34.
Hypoglycaemia occurs due to ethanol's inhibition of gluconeogenesis, especially in children, and may cause lactic acidosis, ketoacidosis, and acute renal failure.
35.
However, metformin is safer than phenformin, and the risk of developing lactic acidosis is not increased except for known high-risk groups.
36.
With continued contractions under anaerobic conditions, the cells undergo lactic acidosis, or the production of lactic acid as a metabolic byproduct.
37.
Signs of lactic acidosis include fast or irregular heartbeat, unusual muscle pain, fatigue, difficulty breathing and stomach pain with nausea and vomiting.
38.
Lactic acidosis sometimes occurs without hypoxia, for example, in rare inborn errors of metabolism where mitochondria do not function at full capacity.
39.
Other names for this syndrome include Finnish lethal neonatal metabolic syndrome ( FLNMS ); lactic acidosis, Finnish, with hepatic hemosiderosis; and Fellman syndrome.
40.
Lactic acidosis ( a toxic buildup of lactic acid ) can be fatal in patients with kidney or liver disease or alcohol problems.
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