With financial support from the Kirin Brewery company, JCF was also able to provide specific medical supplies, such as leukocytosis factor agents for chemotherapy, to Iraq s Central Teaching Hospital and to the Mansour Children's Welfare Teaching Hospital.
32.
The mechanism that causes leukocytosis can be of several forms : an increased release of leukocytes from bone marrow storage pools, decreased margination of leukocytes onto vessel walls, decreased extravasation of leukocytes from the vessels into tissues, or an increase in number of precursor cells in the marrow.
33.
"' Persistent polyclonal B-cell lymphocytosis "'( PPBL ) is an anomaly of the human immune system characterized by mildly elevated levels of white blood cells ( called leukocytosis ), chronic, stable absolute polyclonal B-cell lymphocytosis, elevated polyclonal IgM and binucleated cells.
34.
The term " infectious mononucleosis " was coined in 1920 by Thomas Peck Sprunt and Frank Alexander Evans in a classic clinical description of the disease published in the " Bulletin of the Johns Hopkins Hospital ", entitled " Mononuclear leukocytosis in reaction to acute infection ( infectious mononucleosis ) ".
35.
There is now good evidence that treatment with hematopoietic growth factors including granulocyte colony-stimulating factor ( G-CSF ), which is used to treat AML, and granulocyte-macrophage colony-stimulating factor can cause SS . Lesions typically occur when the patient has leukocytosis and neutrophilia but not when the patient is neutropenic.
36.
As strychnine poisoning progresses, tachycardia ( rapid heart beat ), hypertension ( high blood pressure ), tachypnea ( rapid breathing ), cyanosis ( blue discoloration ), diaphoresis ( sweating ), water-electrolyte imbalance, leukocytosis ( high number of white blood cells ), trismus ( lockjaw ), risus sardonicus ( spasm of the facial muscles ), and opisthotonus ( dramatic spasm of the back muscles, causing arching of the back and neck ) can occur.
37.
There are several clinical features which are unique to C . sordellii : marked leukocytosis ( leukaemoid reaction ), refractory hypotension, severe tachycardia, haemoconcentration, persistent apyrexia and profound capillary leak syndrome ( see entry for " Clostridium novyi " alpha-toxin for details of mechanism . ) In terms of management, there is no hard and fast rule as with most bacterial pathogens but past data reveals C . sordellii susceptibility to beta-lactams, clindamycin, tetracycline and chloramphenicol but resistant to aminoglycosides and sulphonamides.
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