31. During systemic spread the virus is able to gain entry into most tissues with a preference for lymphoid tissues . 32. Her lab's findings led to the development of the WHO Classification of Tumours of the Hematopoetic and Lymphoid Tissues . 33. Originally it was theorized that the micro-environment of lymphoid tissues provided the cues for the preferential homing of lymphocytes. 34. STING is expressed in hematopoietic cells in peripheral lymphoid tissues , including T lymphocytes, NK cells, myeloid cells and monocytes. 35. These B cells then leave the bone marrow and migrate to peripheral lymphoid tissues , such as a lymph node. 36. Postmortem lesions occur in multiple organs, especially in lymphoid tissues and lung, giving rise to the term " multisystemic ". 37. It contains a lot of well-organized lymphoid tissue and most likely evolved as an important part of the immune system. 38. Naive T-cells are not present in high numbers in peripheral tissue, but stay mainly in the circulation and lymphoid tissue . 39. They found IgA producing B cells in the Peyer s patches, intestinal lymphoid tissues and follicles, and mesenteric lymph nodes. 40. TLR10 has been transcriptionally shown to be expressed in secondary lymphoid tissues such as the spleen, lymph nodes and tonsils.
