31. A 2014 Cochrane review found insufficient evidence to determine the effectiveness of psychological versus medical therapy in children. 32. More advanced cases may be resistant or unresponsive to medical therapy , however, and require hair transplantation. 33. It may be the largest single advance in the standards and outcome of medical therapy of all time. 34. Leeching ( medical ) was in Gaelic Ireland, Scotland and elsewhere for millennium a pervasive medical therapy . 35. As a result, problems like low testosterone, which can improve with medical therapy , are left untreated. 36. He said a natural antibiotic made by the ancient bacteria is being analyzed for possible use in medical therapy . 37. In ancient China, medical therapy was often classified as either " external " or " internal " treatment. 38. Likewise, post-menopausal estrogen replacement is safe in patients with prolactinoma treated with medical therapy or surgery. 39. With medical therapy , 1-year survival was 88 % and 5-year survival was 55 %. 40. Several medical therapies have been proposed in the treatment of AIED, with corticosteroid therapy being the most effective.