31. Cabozantinib is approved by the U . S . FDA for medullary thyroid cancer. 32. There is only one current clinical trial that is studying thyroid gland medullary carcinoma. 33. Specifically, they monitor pH change within the medullary interstitual fluid and cerebral spinal fluid. 34. The medullary pyramids contain motor fibers that are known as the corticobulbar and corticospinal tracts. 35. Calcitonin levels remain a valuable marker to detect recurrence of medullary thyroid carcinoma after thyroidectomy. 36. Lymph flows into the medullary sinuses from cortical sinuses, and into the efferent lymphatic vessel. 37. Both syndromes are characterized by pheochromocytoma as well as thyroid cancer ( thyroid medullary carcinoma ). 38. Mantell noticed that the leg bones contained a medullary cavity, a characteristic of land animals. 39. Its fibers acquire their medullary sheaths early, but their connections have not been definitively determined. 40. The flushing that occurs in medullary thyroid carcinoma is indistinguishable from that associated with carcinoid syndrome.