31. Strengthened adhesions between tumour cells reduce the frequency of metastasis . 32. Activation of these metastasis suppressors can potentially block metastasis and improve survival. 33. Activation of these metastasis suppressors can potentially block metastasis and improve survival. 34. There is still no lymph node involvement and no metastasis . 35. Cancer stem cell hypothesis might explain such phenomena as metastasis and remission. 36. When left untreated, metastasis or even death may occur. 37. The device is also approved for the treatment of bone metastasis 38. TET1 levels could be used to detect breast cancer metastasis . 39. Cancer metastasis consists in the fast and uncontrolled division of abnormal cells. 40. Today, B16 melanoma remains an indispensable for metastasis studies.