31. Smoking increases the risk of skin necrosis 12-fold. 32. It is believed the necrosis caused his summer condylar fracture. 33. These hemorrhages are related to tumor necrosis , vascular invasion and neovascularity. 34. TRAIL shows homology to other members of the tumor necrosis factor superfamily. 35. It is on the pathway that activates tumor necrosis factor-alpha. 36. In untreated cases, local necrosis frequently occurs and may require amputation. 37. In most cases, the center of this focus undergoes caseous necrosis . 38. The mechanism is thought to be mediated by tumour necrosis factor inhibition. 39. Interleukin-1 and tumour necrosis factor are involved in cutaneous hyperalgesia. 40. The myositis was associated with hameorrhage, necrosis and degeration.