31. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. 32. This protein is thought to be a negative regulator of AP-1 / ATF transcriptional events. 33. CD109 acts as a negative regulator of the tumor growth factor ? ( TGF-? ) receptor. 34. HDAC11 has been shown to be a negative regulator of IL-10 production in antigen presenting cells. 35. All together, these data indicate that proteases can function as both positive and negative regulators of angiogenesis. 36. It serves as a negative regulator of TGF beta signaling and may limit tgf-beta expression during embryogeneis. 37. NF1 encodes the protein neurofibromin, which appears to be a negative regulator of the ras signal transduction pathway. 38. This work indicated that CDK8 and CDK19 are negative regulators of super-enhancer-associated genes in AML. 39. TspO of Rhodobacter sphaeroides is involved in signal transduction, functioning as a negative regulator of the stress conditions. 40. The proposed mechanism of FMRP s effect upon synaptic plasticity is through its role as a negative regulator of translation.
