31. Pain relief clinics that focused primarily on nerve blocks were pioneered in the United States in the 1930s. 32. Chelly likens the nerve blocks to the Novocain dentists use to deaden a small area in the mouth. 33. The Palm Beach Gardens resident has been through many medical procedures for pain, she said, even nerve blocks . 34. The concept of nerve block sometimes include " central nerve block ", which includes epidural and spinal anaesthesia. 35. The local anesthesia techniques can be either a local field block or a regional nerve block of the scalp. 36. "' Piperocaine "'is a local anesthetic drug developed in the 1920s and used as its hydrochloride infiltration and nerve blocks . 37. Local anesthetic nerve blocks act on the voltage-gated sodium channels that conduct electrical impulses and mediate fast depolarization along nerves. 38. In an effort to minimize the discomfort from the biopsies, he also popularized the use of the periprostatic nerve block . 39. The search for the most effective and least traumatic approach for plexus anesthesia and peripheral nerve blocks continues to this day. 40. One of its surgical techniques is a nerve block , an injection that block pain in a particular region of the body.