31. As a result, the incidence of neural tube defects has dropped by nearly 20 percent. 32. Neuromeres are the segments of the neural tube that establish the embryonic brain during development. 33. Spina bifida, a leading cause of childhood paralysis, is the most common neural tube defect. 34. If the top of the neural tube remains open, a baby's brain does not develop. 35. The plate edges rise dorsally and fold toward the midline to form the neural tube . 36. Worldwide, 300, 000 to 400, 000 babies are born each year with neural tube defects. 37. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure. 38. Analysis can detect neural tube defects and genetic disorders. 39. The central canal represents the adult remainder of the central cavity of the neural tube . 40. Neurula involves the formation of an internal neural tube from an external sheet of cells.