As development continues into neurons the neurofilament triplet proteins ( NF-L : neurofilament low molecular mass, NF-M : neurofilament medium molecular mass, and NF-H : neurofilament high molecular mass ) are expressed in increasing molecular mass order as ?-internexin expression decreases.
32.
As development continues into neurons the neurofilament triplet proteins ( NF-L : neurofilament low molecular mass, NF-M : neurofilament medium molecular mass, and NF-H : neurofilament high molecular mass ) are expressed in increasing molecular mass order as ?-internexin expression decreases.
33.
The disease entities which are now considered subtypes of FTLD-FUS are atypical frontotemporal lobar degeneration with ubiquitinated inclusions ( aFTLD-U ), NIFID ( otherwise known as neurofilament inclusion body disease ) and basophilic inclusion body disease ( BIBD ), which together with ALS-FUS comprise the FUS-opathies.
34.
Seven genes encode for the heavy ( NF-H ), medium ( NF-M ) and light neurofilament ( NF-L ) proteins, nestin and ?-internexin in nerve cells, synemin ? and desmuslin / synemin ? ( two alternative transcripts of the DMN gene ) in muscle cells, and syncoilin ( also in muscle cells ).
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