31. Nuclear membrane staining appears as a fluorescent ring around the cell nucleus and are produced by anti-gp210 and anti-p62 antibodies.32. The nuclear membrane does not disappear, but during metaphase the chromosomes are condensed, often considerably more than in normal mitosis. 33. Therefore, the early stages in the cell cycle, beginning in prophase and until around prometaphase, the nuclear membrane is dismantled. 34. The nucleolus starts moving towards the nuclear membrane at the beginning of prophase, and its disintegration occurs near the nuclear envelope. 35. Further down the IFN? / ? pathway, STAT1 and STAT2 are transported across the nuclear membrane , as depicted in the image. 36. Both cases result in the buildup of farnesylated prelamin A on the nuclear membrane and in the characteristic nuclear LMNA blebbing. 37. This mutated form contains an enfolded nuclear membrane and has a cerebriform shape, resembling the shape and folds of the brain. 38. DNA viruses, such as herpesvirus replicate and assemble in the cell nucleus, and exit by budding through the inner nuclear membrane . 39. NFE2L3 is a membrane bound glycoprotein that is targeted specifically to the endoplasmic reticulum ( ER ) and the nuclear membrane . 40. TMPO alpha is present diffusely expressed with the cell nucleus while TMPO beta and gamma are localized to the nuclear membrane .
