31. Astrocytes are responsible for demyelination and the destruction of oligodendrocytes that is associated with the disease. 32. For instance, SEMA3s modulate the recruitment of oligodendrocyte precursor cells and their differentiation into oligodendrocytes. 33. For instance, SEMA3s modulate the recruitment of oligodendrocyte precursor cells and their differentiation into oligodendrocytes . 34. Galactocerebroside is a marker for oligodendrocytes in the brain, whether or not they form myelin. 35. Hence LINGO1 functions as a negative regulator of neuronal survival, axonal regeneration and oligodendrocyte differentiation. 36. The expression of MYRF is specific to mature, myelinating oligodendrocytes in the MOG drops rapidly. 37. It appears that astrocytes are coupled by gap junctions, both to other astrocytes and to oligodendrocytes . 38. TGF-? have also been observed to induce Oligodendrocyte ( myelin sheath producing cells ) growth. 39. The key characteristic that sets VWM apart from the other leukodystrophies is the presence of foamy oligodendrocytes . 40. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord.