Lumbar puncture or surgical treatment may be required to prevent optic atrophy in cases of intracranial hypertension refractory to treatment with immunomodulators and steroids.
32.
"' Leber s hereditary optic neuropathy "'( LHON ) or "'Leber optic atrophy "'is a complex I of the oxidative phosphorylation chain in mitochondria.
33.
Additionally, PARL is involved in apoptosis through its interactions with the mitochondrial GTPase optic atrophy 1 ( OPA1 ) and the Bcl-2 family-related protein HAX1.
34.
CNS involvement in Beh�et's may lead to intracranial hypertension most commonly due to dural venous sinus thrombosis [ 8-10 ] and subsequent secondary optic atrophy.
35.
The types of neurosyphilis include asymptomatic, acute syphilitic meningitis, meningovascular syphilis, parenchymatous syphilis ( which includes general paresis and tabes dorsalis ), and optic atrophy.
36.
If left untreated, patients ultimately develop late sequel, which may include optic atrophy, retinal arterial narrowing, diffuse retinal pigment epithelial changes, and an abnormal electroretinogram.
37.
However, optic atrophy was the most significant cause of visual impairment identified in 54 percent of patients with ocular Beh�et's disease and permanent visual impairment.
38.
Ocular complications, though rare, are listed as optic atrophy, microphthalmia, pigmentary chorioretinitis, hemeralopia ( decreased vision in bright light ), myopia, strabismus, iris / retinal coloboma.
39.
Rarely it may have ocular complications such as hemeralopia, pigmentary chorioretinitis, optic atrophy or retinal / iris coloboma, having a serious effect on the person's vision.
40.
Vasculitis resulting in occlusion of the vessels supplying the optic nerve may be the cause of acute optic neuropathy and progressive optic atrophy in Beh�et's disease.
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