31. A " Down Beat " profile indicated he had " Osteogenesis ", probably meaning osteogenesis imperfecta. 32. A " Down Beat " profile indicated he had " Osteogenesis ", probably meaning osteogenesis imperfecta. 33. In skeletally immature individuals, the blood supply to the epiphyseal bone is good, supporting both osteogenesis and chondrogenesis. 34. WISP-1 promotes mesenchymal cell proliferation and osteoblastic differentiation, and represses BMP2 and enhances BMP2 function in osteogenesis . 35. David Sillence created the first classification system for Osteogenesis Imperfecta that he later developed further to be the world standard. 36. Although some doctors have prescribed alendronate for children with osteogenesis imperfecta, the Shriners investigators haven't outside the trial. 37. Joint hypermobility syndrome shares symptoms with other conditions such as Marfan syndrome, Ehlers-Danlos Syndrome, and osteogenesis imperfecta. 38. Wormian bones are a marker for some diseases and important in the primary diagnosis of brittle bone disease : osteogenesis imperfecta. 39. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. 40. Allen, 2 1 / 2, suffers from a rare genetic bone defect called osteogenesis imperfecta, or brittle bone disease.