31. BRAF mutations are frequent in papillary carcinoma and in undifferentiated cancers that have developed from papillary tumors. 32. There is ongoing discussion regarding the best management regarding the optimal surgical procedure for papillary thyroid cancer. 33. Prognosis is worse if a mechanical complication such as papillary muscle or myocardial free wall rupture occurs. 34. Of the four main kinds of thyroid cancer, the papillary type is by far the most common. 35. Ebert was diagnosed with papillary cancer, one of the most common and curable types of thyroid cancer. 36. The papillary muscles extend from the walls of the heart to valves by cartilaginous connections called chordae tendinae. 37. A subsequent elevation of the thyroglobulin level is an indication of recurrence of papillary or follicular thyroid carcinoma. 38. The anterior and posterior papillary muscles of the left ventricle attach via chordae tendineae to the mitral valve. 39. Moreover, Ck-19 is widely applied as post-operative diagnostic marker of papillary thyroid carcinoma. 40. In diagnostic immunohistochemistry, the expression of thyroid peroxidase ( TPO ) is lost in papillary thyroid carcinoma.
