Polymer-based perivascular wraps are attracting growing interest for their potential use to deliver nitric oxide and other drugs in the treatment of neointimal hyperplasia.
32.
This membrane lies deep to the pia mater and the subpial space and surrounds the perivascular ( cerebrospinal fluid ( CSF ) must cross the glia limitans.
33.
In the perivascular spaces, the pia mater begins as mesothelial lining on the outer surface, but the cells then fade to be replaced by neuroglia elements.
34.
It is thought to distinguish arterial and venous endothelium, stimulating the production of capillary sprouts as well as in the differentiation of mesenchyme into perivascular support cells.
35.
A scalp biopsy of the 18-year-old sister showed slight follicular plugging, mild perivascular and periadnexal inflammatory cell presence, and normal hair follicles.
36.
In 2002, Mayo Clinic researchers identified an humoral mechanism, targeting a perivascular protein, as the culprit for NMO and in 2004 an unknown specific autoantibody was found.
37.
Upon the clinical application of MRI, it was shown in several studies that perivascular space dilation and lacunar strokes are the most commonly observed histological correlates of signaling abnormalities.
38.
Co-culturing 3T3-L1 pre-adipocytes in 3D with murine endothelial bEND . 3 cells creates a vascular-like network assembly with concomitant lipogenesis in perivascular cells.
39.
Perivascular spaces also play an important role in immunoregulation; they not only contain CD95 receptor, to open up the glia limitans and let T cells into the parenchyma of the brain.
40.
One model suggests that CNS-specific autoimmune T cells which constantly circulate through the cerebrospinal fluid ( CSF ) interact with perivascular dendritic cells that reside at the choroid plexus and meninges.
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