31. Tissue biopsies of SPB and extramedullary plasmacytoma are used to assess the phenotype of the plasma cells . 32. Within the synovium collected, plasma cells and T-lymphocytes were the primary inflammatory cells present. 33. A bone marrow biopsy is usually performed to estimate the percentage of bone marrow occupied by plasma cells . 34. About 10 % of plasma cells survive to become long-lived antigen-specific memory B cells. 35. TLR10 has also been shown to be produced intracellularly in neutrophils and B cells differentiating into plasma cells . 36. XBP1 is also essential for differentiation of plasma cells ( a type of antibody secreting immune cell ). 37. When there are more abundant plasma cells , more antibodies are then produced as a result of this. 38. Common variable immunodeficiency is thought to be due to a problem in the differentiation from lymphocytes to plasma cells . 39. Antibodies, Y-shaped proteins created by plasma cells , recognize and neutralize any pathogens in the body. 40. In August 2009, Nerat was diagnosed with multiple myeloma, a type of cancer which affects plasma cells .