31. Higher plasma concentrations also lead to cardiovascular effects, though cardiovascular collapse may also occur with low concentrations. 32. In fasting persons, bioavailability is 25 %, and highest blood plasma concentrations are reached after one hour. 33. Despite the very low plasma concentration , variants within apolipoprotein A5 are potent determinants of plasma triglyceride levels. 34. The average blood-to-plasma concentration ratio was 0.636. 35. This could increase the plasma concentration of both drugs by inhibiting metabolism and increasing blood serum concentrations. 36. Clemastine is rapidly absorbed from the gastrointestinal tract and peak plasma concentrations are attained in 2 4 hours. 37. Cortisol is an important stress hormone; its plasma concentrations increase greatly when subjected to high levels of stress. 38. Pregabalin is rapidly absorbed when administered on an empty stomach, with peak plasma concentrations occurring within one hour. 39. Following an oral single dose of 20 mg peak plasma concentrations are reached within 1 to 2 hours. 40. When taken with fatty food, highest plasma concentrations are reached after two hours, and the cytochrome P450 enzymes.
