31. Plasmin is inactivated by proteins such as sterically shielded, thus substantially decreasing the plasmin 's access to protein substrates. 32. Promatrilysin ( Pro-MMP7 ) is converted from the latent form to the active form by endoproteinases, and plasmin . 33. Plasmin is a fibrolytic enzyme that aids in the breakdown of blood clots and is used clinically for that exact purpose.34. Tissue-type plasminogen activator ( tPA ) is a serine proteinase that transforms plasminogen into its activated form, plasmin . 35. To be specific, tPA cleaves the zymogen plasminogen at its Arg561-Val562 peptide bond, into the serine protease plasmin . 36. Tranexamic and aminocaproic acids inhibit the conversion of plasminogen to plasmin , plasmin being the agent of fibrin breakdown in blood clots. 37. Tranexamic and aminocaproic acids inhibit the conversion of plasminogen to plasmin, plasmin being the agent of fibrin breakdown in blood clots. 38. It exhibits an anti-plasmin inhibitory effect It also exhibits a cytoprotective effect against oxidative stress in Chinese hamster lung fibroblasts. 39. In contrast, plasmin further stimulates plasmin generation by producing more active forms of both tissue plasminogen activator ( tPA ) and urokinase. 40. In contrast, plasmin further stimulates plasmin generation by producing more active forms of both tissue plasminogen activator ( tPA ) and urokinase.
