31. Urokinase plasminogen activator receptor ( uPAR ) is a cofactor for plasminogen activation by urokinase plasminogen activator. 32. Urokinase plasminogen activator receptor ( uPAR ) is a cofactor for plasminogen activation by urokinase plasminogen activator. 33. Urokinase plasminogen activator receptor ( uPAR ) is a cofactor for plasminogen activation by urokinase plasminogen activator. 34. The serum proteins transferrin, fibronectin, and plasminogen are also known to bind IGFBP-3. 35. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen -bound zymogen. 36. This drug is made by transgenic bacteria and it converts plasminogen into the clot-dissolving enzyme plasmin. 37. Hep G2 is a alpha 2-macroglobulin, alpha 1-antitrypsin, transferrin, and plasminogen . 38. Cleavage of the von Willebrand factor inhibits platelet aggregation and of plasminogen produces an angiostatin fragment preventing angiogenesis. 39. Thus inhibitors of the various components of the plasminogen activation system have been sought as possible anticancer drugs. 40. Interestingly, injection of tissue plasminogen activator ( a fibrinolytic drug ) in the CSF improved glymphatic functioning.
