Individuals with familial adenomatous polyposis ( FAP ), a syndrome of early-onset colonic polyps and adenocarcinoma, frequently develop hepatoblastomas.
32.
Other conditions consisting of multiple hamartomatous polyps of the digestive tract include Peutz-Jeghers syndrome, juvenile polyposis, and Cowden disease.
33.
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli ( APC ) protein-binding EB1 gene family.
34.
He is a co-author of the Bethesda Guidelines for the diagnosis of Hereditary non-polyposis colorectal cancer ( HNPCC ).
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One relatively rare form of the disease ( familial polyposis ) is strongly genetic, but many cases of colorectal cancers have inherited components.
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Examples of proteins that contain armadillo repeats include ?-importin, plakoglobin, adenomatous polyposis coli ( APC ), and many others.
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The serrated polyposis syndrome ( SPS ) is a relatively rare condition characterized by multiple and / or large serrated polyps of the colon.
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Each girl had a 50 percent chance of inheriting the familial polyposis gene, and each has been examined regularly for signs of the disease.
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From 1996 to 1998, Searle, the maker of Celebrex at that time, conducted a study with patients who had familial adenomatous polyposis.
40.
Multiple adenomatous polyps often result from familial polyposis coli or familial adenomatous polyposis, a condition that carries a very high risk of colon cancer.
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