31. Rarely, the signs and symptoms of variegate porphyria can begin in infancy or early childhood. 32. The activity of this enzyme is reduced by 50 percent in most people with variegate porphyria . 33. People who have these mutations are also at an increased risk of developing porphyria cutanea tarda. 34. More than 100 mutations that can cause variegate porphyria have been identified in the PPOX gene. 35. It is an extremely rare cause of porphyria , with less than 10 cases ever reported. 36. He orders that Tracy be treated for porphyria and that Jeremy's bowel be biopsied. 37. King George III was a man of very strong opinions even when not affected by porphyria . 38. If the diagnosis of hereditary porphyria is correct, it may have continued among descendants of Victoria. 39. It has a similar presentation to porphyria cutanea tarda ( PCT ), but with earlier onset. 40. Later in life, these individuals may present with photosensitivity similar to that found in cutaneous porphyrias .
