The coagulant in the venom directly activates factor X, which turns prothrombin into thrombin in the presence of factor V and phospholipid.
32.
Historically, thromboplastin was a lab reagent, usually derived from placental sources, used to assay prothrombin times ( PT time ).
33.
FXa cleaves prothrombin to its active form thrombin, which then acts to convert soluble fibrinogen to insoluble fibrin and to activate platelets.
34.
These tests include prothrombin time ( PT / INR ), aPTT, albumin, bilirubin ( direct and indirect ), and others.
35.
Prothrombin G20210A is not usually accompanied by other factor mutations ( i . e ., the most common is factor V Leiden ).
36.
If the INR is greater than 1.5 to 1.8 correction with fresh frozen plasma or prothrombin complex may decrease mortality.
37.
The enzyme is also involved in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
38.
Anticoagulant related haemorrhage was extremely rarely reported because few patients received prothrombin depressants for long periods of time ( Sublata Causa Tollitur Effectus ).
39.
"' Prothrombin activator "'is a complex of a dozen blood coagulation factors that functions in catalyzing prothrombin into thrombin.
40.
"' Prothrombin activator "'is a complex of a dozen blood coagulation factors that functions in catalyzing prothrombin into thrombin.
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