31. Most drugs that can disrupt folic acid are known as dihydrofolate reductase inhibitors. 32. It binds dihydrofolate reductase and prevents synthesis of tetrahydrofolate. 33. HMG-CoA reductase is an important developmental enzyme. 34. The mechanism of Glutathione Reductase in sustaining the oxidative burst is still unknown. 35. In particular, Glutathione reductase contributes to plants'response to abiotic stress. 36. Glutathione reductase was first purified in 1955 at Yale by E . Racker. 37. This results in an accumulation of deoxy-GTP which inhibits ribonucleotide reductase . 38. Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. 39. Lubiprostone is rapidly metabolized by reduction / oxidation, mediated by carbonyl reductase . 40. Dihydroflavonol 4-reductase is an enzyme part of the lignin biosynthesis pathway.
