Because the terms on the action of the scientist Isaac Newton claimed : " Every action has an equal and reversible reaction . " Not only on this planet of energy, but also from the same source of social life there may be Action.
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It now discusses the phosphorylation-dephosphorylation reversible reaction, explains the mechanism of the enzyme phosphatase, and alludes to later sections which delve into the role of the process in disease and molecular biology techniques . talk ) 03 : 35, 11 May 2013 ( UTC)
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The reaction is similar to the reaction catalysed by pyruvate kinase, which also converts pyruvate to PEP . However, pyruvate kinase catalyses an irreversible reaction, and does not consume ATP . By contrast, PPDK catalyses a reversible reaction, and consumes 1 molecule of ATP for each molecule of pyruvate converted.
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Lesch-Nyhan syndrome is caused by a deficiency in hypoxanthine-guanine phosphoribosyltransferase or HGPRT, the enzyme that catalyzes the reversible reaction of producing guanine from GMP . This is a sex-linked congenital defect that causes overproduction of uric acid along with mental retardation, spasticity, and an urge to self-mutilate.
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"' Fructose-bisphosphate aldolase "'( ), often just "'aldolase "', is an enzyme catalyzing a reversible reaction that splits the aldol, fructose 1, 6-bisphosphate, into the triose phosphates dihydroxyacetone phosphate ( DHAP ) and glyceraldehyde 3-phosphate ( G3P ).
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But his best known contribution to general chemistry is his work on the phenomena of reversible reactions, which he comprehended under a general theory of " dissociation . " He first took up the subject about 1857, and it was in the course of his investigations on it that he devised the apparatus known as the " Deville hot and cold tube ."
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More generally the SKIE for reversible reactions can be " normal " one way and " inverse " the other if bonding in the transition state is midway in stiffness between substrate and product, or they can be " normal " both ways if bonding is weaker in the transition state, or " inverse " both ways if bonding is stronger in the transition state than in either reactant.
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"' Yablonsky theorem "'. " A system of reactions with some irreversible reactions is a limit of systems with detailed balance when some constants tend to zero if and only if ( i ) the reversible part of this system satisfies the principle of detailed balance and ( ii ) the convex hull of the stoichiometric vectors of the irreversible reactions has empty intersection with the linear span of the stoichiometric vectors of the reversible reactions ."
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