31. G proteins are a family of intracellular proteins capable of mediating signal transduction pathways. 32. Bitter taste has many different receptors and signal transduction pathways. 33. These surface immunoglobulin ( sIg )-associated molecules facilitate signal transduction . 34. TRAF3 may play a critical role in OX40-mediated signal transduction . 35. These interactions promote cell adhesion and regulation of signal transduction . 36. The insulin signal transduction pathway begins when insulin binds to the insulin receptor proteins. 37. Further signal transduction depends on the type of G protein. 38. This dimerization has been proposed to play an important role in CD36 signal transduction . 39. A signal transduction cascade results in the secretion of first and second group antagonists. 40. PDEs are therefore important regulators of signal transduction mediated by these second messenger molecules.