This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene.
32.
This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane.
33.
This became known as a red blood cell " ghost " ( spectre ), and so the major protein of the ghost was named spectrin.
34.
The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin.
35.
In a canine model of hypothermic circulatory arrest, alpha II-spectrin breakdown products have shown to be relevant markers of neurologic injury post-cardiac surgery.
36.
Arp1 has been shown as the domain for dynactin binding to membrane vesicles ( such as Golgi or late endosome ) through its association with ?-spectrin.
37.
Based on these structural features it is thought that SPTBN5 is likely to form heterodimers and oligomers with alpha-spectrin and to interact directly with cellular membranes.
38.
The precise [ [ mode of action is not known, but it is thought to act by affecting spectrin-like proteins in the cytoskeleton of oomycetes.
39.
The protein encoded by the ANK3 gene is a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton.
40.
In the light microscope the basic shape of the red blood cell could still be seen as the spectrin containing submembranous cytoskeleton preserved the shape of the cell in outline.
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