It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes M transition in fruitfly but in mice the primary defect is postmeiotic at round spermatid stage.
32.
This gene is predominantly expressed in the testis and in mouse, tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules, indicating that it may play a role in spermatogenesis.
33.
However, sertoli cells form tight junctions that separate SSCs and spermatogonia in contact with the basement membrane from the spermatocytes and spermatids to create a basal and an adluminal compartment, whereby differentiating spermatocytes must traverse the tight junctions.
34.
Expression of CRMPs-1,-4, and-5 in the adult testis is detected only in the cell spermatid stage and CRMP-2 mRNA is found in lung tissue of the fetal mouse and adult human.
35.
These junctions are located at the Sertoli Sertoli cell interface and Sertoli-elongating spermatid interface, which occur during the seminiferous epithelial cycle of spermatogenesis . There must be vast reconstructing of the anchoring junctions such as the ectoplasmic specializations within the testies.
36.
Sustentacular cells are supporting cells of the seminiferous tubules of the testis, responsible for the differentiation of spermatids, the maintenance of the blood-testis barrier, and the secretion of inhibin, androgen-binding protein, and Mullerian-inhibiting factor.
37.
Hewitson, L ., Martinovich, C ., Simerly, C ., Takahashi, D ., Schatten, G . ( 2002 ) Intracytoplasmic injection of rhesus testicular sperm ( TESE-ICSI ) and elongated spermatids ( ELSI ) results in healthy offspring.
38.
Mutations in " Mtap2 ", a microtubule-associated protein, as observed in " repro4 " mutant spermatocytes, have been shown to arrest spermatogenesis progress during the prophase of Meiosis I . This is observed by a reduction in spermatid presence in " repro4 " mutants.
39.
The purpose of this fluid is ( among other things, undoubtedly ) to lubricate the urethra and create a favorable environment for healthy sperm to travel down the urethra and into the vagina . ( There appear to be many factors which collectively create this favorable environment : pH, lubrication, inactive spermatids, binders etc . ).
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