31. Homoserine is an intermediate in the biosynthesis of threonine , isoleucine, and methionine. 32. This gene encodes a member of the RSK family of serine / threonine kinases. 33. The encoded protein is a member of the serine / threonine protein kinase family. 34. Threonine is an amino acid found in certain meats, nuts, and seeds.35. There are 32 predicted serine phosphorylation sites, 5 threonine , and 3 tyrosine. 36. The threonine and superfamilies, and some superfamilies show divergent evolution to multiple different nucleophiles. 37. Full kinase activity requires an activating phosphorylation on a threonine adjacent to the active site. 38. One major pathway leads to the activation of the serine / threonine kinase, Akt. 39. Threonine dehydrogenase catalyzes the deamination and dehydration of threonine to 2-ketobutyrate and ammonia.40. Threonine dehydrogenase catalyzes the deamination and dehydration of threonine to 2-ketobutyrate and ammonia.