Syphilis is now relatively rare, but the tertiary stage can cause diffuse glossitis and atrophy of lingual papillae, termed " syphlitic glossitis ", It is caused by Treponema pallidum and is a sexually transmitted infection.
32.
TIGR followed these accomplishments with the genomes of the pathogenic bacteria " Borrelia burgdorferi " ( which causes Lyme Disease ) in 1997 and " Treponema pallidum " ( which causes syphilis ) in 1998.
33.
One example is the production of 1-butanol in " Synechococcus elongatus " using enzymes from " Clostridium acetobutylicum ", " Escherichia coli " and " Treponema denticola ".
34.
Despite the extreme age of the spirochetes, which have existed for well over 100 million years, Treponema pallidum presumably learned only recently how to infect humans, a host with a mere 100, 000-year ancestry.
35.
With Paul Blocq he was the first to describe senile plaques and with Romanian neurologist Ion Minea confirmed in 1913 Hideyo Noguchi's discovery of " Treponema pallidum " in the brain in patients with general paresis.
36.
Born in R�seningken, East Prussia, he co-discovered, with Erich Hoffmann in 1905, the causative agent of syphilis, " Spirochaeta pallida " ( also known as " Treponema pallidum " ).
37.
However, after four years, the team were asked to also oversee the curation and annotation of the genomes of seven additional bacterial species ( Chlamydia, Chlamydophila, Haemophilus, Mycoplasma, Neisseria, Treponema, and Ureaplasma ).
38.
The PPi-dependent phosphofrucktokinase sequences are only available from three organisms in the " Spirochaetales " order : " Spirochaeta thermophila ", " Borrelia burgdorferi ", and " Treponema pallidum ".
39.
Like other spirochetes, such as " Treponema pallidum " ( the agent of syphilis ), " B . burgdorferi " has an axial filament composed of flagella which run lengthways between its cell wall and outer membrane.
40.
Syphilis ( caused by infection with " Treponema pallidum " ) is passed from person to person through direct contact with a syphilis sore; these occur mainly on the external genitals, or in the vagina, anus, or rectum.
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