41. Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. 42. Of those, about 2 10 % have cancer, while 20 30 % have adenomas . 43. Adenomas are more common, making up 91 percent of perianal gland tumors in one study.44. He established three pathognomonic clinical signs for the condition : epilepsy, idiocy and adenoma sebaceum. 45. MEN1 pituitary tumours are adenomas of anterior cells, typically prolactinomas or growth hormone-secreting. 46. :Pituitary adenomas can cause the growth of ancillary and facial hair at virtually any age. 47. An example of PAS-D in use is in showing duodenal metaplasia in duodenal adenomas . 48. Further, MMP7 is involved in converting colorectal adenomas into malignant state and facilitating the growth. 49. Some adenomas grow slowly and symptoms of GH excess are often not noticed for many years. 50. These tests are based on the glucocorticoid sensitivity of pituitary adenomas compared to non-pituitary tumors.