41. These responses are important in climate adaptation and as a cause of constipation with elevated aldosterone . 42. Age of diagnosis of males with CAH varies and depends on the severity of aldosterone deficiency. 43. Renin but not aldosterone is elevated. 44. 21-hydroxylase deficiencies, an enzyme used by the body to produce cortisol and aldosterone . 45. They inhibit angiotensin-converting enzyme, which is part of the renin angiotensin aldosterone system. 46. These mineralocorticoids cross-react with the aldosterone receptor, activating it and raising blood pressure. 47. Intravenous administration QRFP caused release of aldosterone , suggesting that QRFP and GPR103 regulate adrenal function. 48. Aldosterone synthase is a steroid hydroxylase cytochrome P450 oxidase enzyme involved in the generation of aldosterone.49. Aldosterone synthase is a steroid hydroxylase cytochrome P450 oxidase enzyme involved in the generation of aldosterone . 50. Aldosterone synthase is found within the zona glomerulosa at the outer edge of the adrenal cortex.
