41. Gliotransmission can also occur between two types of glial cells : astrocytes and microglia. 42. Astrocyte dysfunction can contribute to multiple neurological disorders.43. This discovery showed that astrocytes likely play an important role in learning and memory. 44. Such discoveries have made astrocytes an important area of research within the field of neuroscience. 45. After the injury, astrocytes can shrink, causing parts of the brain to atrophy. 46. Abnormally shaped astrocytes with fibrile infections are very prevalent throughout the capillaries in the brain. 47. Additionally, CD47 blocking antibodies inhibit proliferation of unstimulated astrocytoma cells but not normal astrocytes . 48. In addition, It can also promote glutamate release and block its reuptake by astrocytes . 49. In severely degenerated areas there are many large, reactive astrocytes filled with glial fibrils. 50. In contrast there were no apparent effects on the production of new astrocytes or oligodendrocytes.
