41. Biotin deficiency can result in behavioral disorders, lack of coordination, learning disabilities and seizure.42. This enzyme participates in biotin metabolism. 43. These oligos are labeled with biotin . 44. The catalytic subunit of all four enzyme porters are biotin -containing multi-subunit enzymes. 45. Biotin is important in fatty acid synthesis, branched-chain amino acid catabolism, and gluconeogenesis.46. Biotinylation will immobilize luciferase on the cell-surface by binding to a streptavidin-biotin complex. 47. This may be due, in part, to the influence of biotin on fatty acid biosynthesis. 48. This process is often used in labeling saccharides with fluorescent molecules or other tags such as biotin . 49. "' Photobiotin "'is a derivative of biotin used as a biochemical tool. 50. This may be overcome through the use of a biotin -avidin or biotin-streptavidin bridge.