41. Calmodulin belongs to one of the two main groups of calcium-binding proteins, called EF hand proteins.42. Dopamine receptor activation of Ca2 + / calmodulin -dependent protein kinase II can be cAMP dependent or independent. 43. Calmodulin may activate calcium-calmodulin-dependent protein kinases, or may act directly on other effector proteins.44. Calmodulin may activate calcium-calmodulin -dependent protein kinases, or may act directly on other effector proteins. 45. CapZ is not regulated by calcium or calmodulin , as seen with other capping proteins, such as Gelsolin. 46. This calcium then interacts with calcineurin and calcium / calmodulin -dependent kinases that in turn activate transcription factors. 47. To overcome such issues, Tsien's group also developed the calmodulin -based sensor, named Cameleon. 48. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin . 49. Opening of the L-type calcium channel causes influx of extracellular Ca 2 +, which then binds calmodulin . 50. Those that belong to the EF-hand superfamily such as Calmodulin and Calcineurin have been linked to transcription regulation.
