41. There is currently no other known modifications necessary to activate the proenzyme and enable catalytic activity . 42. The association of all four monomers allows for the catalytic activity at each possible active site. 43. Improvement of the assayed activity can be due to improvements in enzyme catalytic activity or enzyme concentration. 44. Biochemical assays require a catalytic activity of the protein in question as well as a specific assay. 45. A problem with transition state analogue selection approach is that catalytic activity is not a screening criterion. 46. Current evidence suggests that there is an overrepresentation of NAT pairs in genes that have catalytic activity . 47. A second method of increasing the catalytic activity of platinum is to alloy it with other metals. 48. Some abzymes have been engineered to use metal ions and other cofactors to improve their catalytic activity . 49. It was found that increased electronegativity of the ligands on the palladium nanoparticles increased their catalytic activity . 50. MIF contains two motifs with catalytic activity .