Mercury irreversibly inhibits selenium-dependent enzymes ( see below ) and may also inactivate catechol-" O "-methyl transferase.
42.
In 1958, Axelrod also discovered and characterized the enzyme catechol-O-methyl transferase, which is involved in the breakdown of catecholamines.
43.
One mechanism proposed by Eicken et al . is based on the crystal structure of catechol oxidase purified from " Ipomoea batatas ".
44.
While a number of inhibitory strategies exist such as high temperature treatments ( 70-90 o C ) to eliminate catechol oxidase catalytic activity,
45.
In this respect, these enzymes are reminiscent of the intradiol catechol dioxygenases whereby the metal centers activate the substrate for subsequent reaction with dioxygen.
46.
Heating catechin past its point of decomposition releases pyrocatechol ( also called catechol ), which explains the common origin of the names of these compounds.
47.
Other developing agents in use are p-aminophenol, glycin ( N-( 4-hydroxyphenyl ) glycine ), pyrogallol, and catechol.
48.
Catechol-" O "-methyltransferase is involved in the inactivation of the catecholamine neurotransmitters ( dopamine, epinephrine, and norepinephrine ).
49.
"' Catechol oxidase "'is a copper oxidase that contains a type 3 di-copper reduction of molecular oxygen to water.
50.
Tolcapone inhibits the catechol-O-methyltransferase ( COMT ) enzyme, which degrades dopamine and levadopa, thereby prolonging the therapeutic effects of levodopa.
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