41. Proof : Some studies show that chondroitin stops joint degeneration, improves joint function and eases pain. 42. Some doctors suspect this may at least partly explain why people find relief from glucosamine and chondroitin . 43. Multiple doses of 800 mg in patients with osteoarthritis do not alter the kinetics of chondroitin sulfate. 44. The bioavailability of chondroitin sulfate ranges from 15 % to 24 % of the orally administered dose. 45. In 1989, Zimmermann and Ruoslahti cloned and sequenced the core protein of fibroblast chondroitin sulfate proteoglycan. 46. The metabolic pathways : chondroitin sulfate biosynthesis, sulfur metabolism, and the biosynthesis of glycan structures. 47. The systematic name of this enzyme class is "'chondroitin AC lyase " '. 48. The systematic name of this enzyme class is "'chondroitin B lyase " '. 49. Glucosamine probably works by stimulating the cells that make cartilage, and chondroitin , by inhibiting cartilage breakdown. 50. That also means daily vitamins and supplements with chondroitin and glucosamine ( up to three a day ).