41. Coenzyme B 12 features a reactive C-Co bond that participates in the reactions.42. -- Coenzyme Q-10. 43. It is a step down a long road to the many potential benefits of this coenzyme . 44. Coenzymes are usually continuously regenerated and their concentrations maintained at a steady level inside the cell.45. One central coenzyme is adenosine triphosphate ( ATP ), the universal energy currency of cells. 46. The donor is often a coenzyme . 47. The catabolism of the methyl compounds is mediated by methyl transferases to give methyl coenzyme M. 48. Initially, Lynen found that acetate activated by Coenzyme A was needed to start the process. 49. Defects in the " ACAD8 " gene cause isobutyryl-coenzyme A dehydrogenase deficiency. 50. Cell-free biosystems can be prepared by mixing a number of purified enzymes and coenzymes .