41. Nonetheless, antibodies against the signal sequence targeted only the cytoplasmic form. 42. MUC1 cytoplasmic tail has been shown to bind to p53. 43. MUC1 cytoplasmic tail is shuttled to the mitochondria through interaction with hsp90. 44. Isoform 1 is bound to the cytoplasmic side of the endoplasmic reticulum. 45. In prokaryotes, they are localized to the cytoplasmic membranes. 46. The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. 47. An insertion variant in exon 1 alters the cytoplasmic tail. 48. This cytoplasmic tail provides docking sites for numerous signaling intermediates. 49. Dsh is a cytoplasmic phosphoprotein that acts directly downstream of frizzled receptors. 50. The cytoplasmic and nuclear pools have distinct functions and regulation.
