41. Elevated concentrations of the enzyme lactate dehydrogenase ( LDH ) may be detected. 42. An estimated 400 million people have glucose-6-phosphate dehydrogenase deficiency. 43. The areas surrounding the phosphorylation sites on pyruvate dehydrogenase are shown in red. 44. The dehydrogenase activity of enoyl-CoA occurs in the carboxyl-terminal. 45. The first box shows the overall isocitrate dehydrogenase reaction. 46. Chromalveolates share similar glyceraldehyde 3-phosphate dehydrogenase proteins. 47. Isoleucine forms a negative feedback loop with threonine dehydrogenase . 48. PDK can phosphorylate a serine residue on pyruvate dehydrogenase at three possible sites. 49. Ethanol s affinity for CYP2E1 is lower than its affinity for alcohol dehydrogenase . 50. Saccharopine dehydrogenase EC reduced by NADPH to give saccharopine.