Mutagenesis experiments have shown that the modification is necessary for the proper formation of ionizing radiation induced foci in response to double strand breaks, but is not required for the recruitment of proteins to the site of DSBs.
42.
:: : But I stated : " Experiments showed that ionizing radiation cause DNA double strand breaks at a rate of 35 double strand breaks per cell per Gray ", clearly the primary source state exactly that.
43.
:: : But I stated : " Experiments showed that ionizing radiation cause DNA double strand breaks at a rate of 35 double strand breaks per cell per Gray ", clearly the primary source state exactly that.
44.
*" These enzymes are attracted to double strand breaks, search for sequence similarity between the duplex strands and catalyze formation of a Holliday junction, branch migration, and resolution . " This sentence is a big jumble.
45.
After plating on selective plates and growing at 37 o C, they observed no colony formation on the LB plates containing chloramphenicol indicating loss of the pCas9cr4 plasmid due to a Cas9-mediated double strand break in the plasmid.
46.
Resolution can occur in either a horizontal or vertical fashion during homologous recombination, giving patch products ( if in same orientation during double strand break repair ) or splice products ( if in different orientations during double strand break repair ).
47.
Resolution can occur in either a horizontal or vertical fashion during homologous recombination, giving patch products ( if in same orientation during double strand break repair ) or splice products ( if in different orientations during double strand break repair ).
48.
These include chemoprotective effects from environmental toxins, anti-inflammatory effects, protection from UV induced photocarcinogenesis, protection from sunburn, protection from UVB-induced epidermal hyperplasia, and DNA repair for UV induced DNA damage ( double strand breaks ).
49.
For example, high energies can induce a double strand break while much more sedate chemical reactions like thymine dimers from even UV light can lead to the modification of a single base pair . talk ) 23 : 43, 8 November 2016 ( UTC)
50.
*" These enzymes are attracted to double strand breaks, search for sequence similarity between the duplex strands . . . " How about " Attracted to double strand breaks in DNA, these enzymes search for sequence similarity between the duplex strands . . ."
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