41. Studies on both rats and humans have demonstrated that APC reduces endotoxin -induced pulmonary injury and inflammation. 42. Bt cotton was created through the addition of genes encoding toxin crystals in the Cry group of endotoxin . 43. Endotoxins may become pyrogenic when released into the bloodstream or other tissue where they are not usually found.44. Currently, the method of choice for endotoxin detection is the Limulus Amebocyte Lysate ( LAL ) test. 45. The endotoxin then washes through the column, and a pure target is later eluted off the column. 46. When he snapped the slurry-dipped gloves in the lab, he also found endotoxin in the air. 47. The researchers also measured the levels of a substance called endotoxin in dust from the children's mattresses. 48. "Endotoxin is just unbelievable in how fast it can cause a reaction, " he said. 49. In resting subjects, endotoxin induced a 2-to 3-fold increase in circulating levels of TNF?. 50. Endotoxin activates the Hageman factor ( clotting factor XII ), which causes disseminated intravascular coagulation ( DIC ).